Computational Neuroscience   Neuronal Canonical Cortical Circuits: The laminar architecture of the mammalian cortex is known to exhibit a repetitive skeletal structure. I am interested in understanding how these circuits contribute to generating large-scale electrical phenomena in the brain such as the electroencephalogram (EEG). In contrast to earlier black-box models of EEG, I look at a six-layer neurophysiological circuit where neural oscillatory behavior can be generated and modulated according to the vigilance state as well as pathological conditions (seizures). Particular focus is given to the role of layer 5 neural populations and interconnections. (relevant pubs)

Resonance phenomena:  It has been demonstrated that recruitment of neural populations into various cognitive tasks could be achieved at preferred frequencies which produce what is known at "resonant"  states or augmenting responses. I am interested in dissecting, by way of simplified compartmental models, the role of layer 5 cells in producing augmenting response and the conditions under which such responses could be obtained. (relevant pubs)

Object recognition in the rat somatosensory system: I am recently investigating and modeling the role of different subsystems in the barrel cortex of rats in conducting object recognition and the adaptability of such tasks under varying whisking speeds. (relevant pubs)

Information coding in neural systems. Investigating the capacity of neural populations to store and transmit information and various coding schemes (time, rate and spatial codes). (relevant pubs)

Electrical Engineering    Dynamic modeling for signal  processing: I am interested in understanding  biological one- and two-dimensional signals using system identification techniques. This systems-level view of signals could provide an additional component in aiding decision making and classification. (relevant pubs)   Biomimetics: developing signal processing algorithms to extract information from biological signals, such as brain computer interface and neural prosthetic devices. (relevant pubs)

Publications:   Journals:

Conferences/meetings

1. Sara I Khaddaj, Ibrahim C Abou-Faycal, Fadi N. Karameh, "A Unified Information Flow model of Poisson Type Brain Neural Network Activity ",  Proceedings of the 47th IEEE Control and Decision Conference, 9-11 Dec 2008, pp 2018-2024.

2. Fadi Bitar, Nasr Madi, Edmond Ramly, Mazen Saghir, Fadi N. Karameh, "A Portable MIDI Controller Using EMG-Based  Individual Finger Motion Classification", Proceedings of the 2007 IEEE Biomedical Circuits and Systems Conference (BioCAS 2007), Canada, 27-30 Nov 2007, pp 138 - 141.

3. Fadi N. Karameh, Steve Massaquoi, "A Model for Nonlinear Motor Cortical Integration and its Relation to Movement Speed Profile Control", Proceedings of the 27th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (IEEE-EMBS2005), Shanghai, September 2005, pp 4331 - 4336.

4. Fadi N. Karameh, "Modeling the Role of Cortical Layer 5 Pyramidal Cells in Integrating First and Higher Order Thalamocortical Network Activity in the Rat Somatosensory Cortex", Program No 586.3. 2007 Abstract Viewer/Itinerary Planner, Washington DC: Society for Neuroscience, 2007. Online.

5. Fadi N. Karameh, Munther A. Dahleh, Steve G. Massaquoi, "A Model of the Neuronal Origins of Cortically-generated Augmenting Responses", Program No. 272.9. 2005 Abstract Viewer/Itinerary Planner, Washington DC: Society for Neuroscience, 2005. Online.

6. Fadi N. Karameh, Munther A. Dahleh, Emery N. Brown, Steve G. Massaquoi, "A Model of the Cortical Basis of Multiple Alpha Rhythms'',  Program No. 934.21. 2003 Abstract Viewer/Itinerary Planner, Washington DC: Society for Neuroscience, 2003. Online.

7. Fadi N. Karameh, Munther A. Dahleh, Emery N. Brown, Steve G. Massaquoi, "A Cerebral Cortical Neuronal Model Simulating Principle Slow Features of Cortical EEG'', Program No. 276.1. 2002 Abstract Viewer/Itinerary Planner, Washington DC: Society for Neuroscience, 2002. Online.

8. Fadi N. Karameh and Munther A. Dahleh, "Automated Classification of EEG Signals in Brain Tumor Diagnostics'',  Proceedings of the American Control Conference, Chicago, IL, 2000.

Other

1. Fadi N. Karameh, "A Model for Cerebral Cortical Neuronal Group Electric Activity and its Implications for Cerebral Function'',  LIDS-TH-2553, MIT, 2002.

2. Fadi N. Karameh, "On-line Identification and Control Algorithm of a System with Jump Parameters Using Wavelets'', LIDS-TH-2340, MIT, 1996.